Ken, interesting that you have designed bridges. You will be aware that long bridges are designed to flex, otherwise they would break up under wind stress. Longer vehicles are designed to flex to some degree too, as do most other vehicles with a chassis.
Monocoque construction largely put an end to chassis use in cars, and they continue to make cars stiffer, with thinner metal, and lighter weight, since that time. Whether this is intrinsically a good thing is quite another matter. As you rightly state: "do as much as you can with the minimum amount of material to ensure the thing doesn't bend, twist or fall apart"is indeed the order of the day. Minimum cost also figures greatly.
Monocoque construction largely put an end to chassis use in cars, and they continue to make cars stiffer, with thinner metal, and lighter weight, since that time. Whether this is intrinsically a good thing is quite another matter. As you rightly state: "do as much as you can with the minimum amount of material to ensure the thing doesn't bend, twist or fall apart"is indeed the order of the day. Minimum cost also figures greatly.